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Foregen and the Science of Regeneration with Tyler Drzod and Eric Cunningham

March 30, 2021 By Brendon Marotta

In this episode, I talk to two members of Foregen, an organization dedicated to regenerating the human foreskin.

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Tyler Drzod, Chief Operation Officer, and Eric Cunningham, Chief Science Officer, give an in-depth explanation of the science of regeneration, the structure of Foregen, and the possibilities for the future.

Topics discussed in this episode: 

  • [1:03] Explaining Foregen to new people
  • [2:15] How does Foregen plan to regenerate the human foreskin?
  • [5:50] How Foregen acquires foreskin scaffolding and foreskin they can de cellularize
  • [7:45] Attaching the foreskin scaffolding to a human being
  • [9:45] What kind of experimentation is needed?
  • [11:10] Previous reconstruction of the entire penile shaft
  • [12:25] Previous breakthroughs in regeneration technology
  • [14:20] Who are the experts at Foregen?
  • [19:50] What is the financial/business structure of Foregen?
  • [24:25] How much money will it take to achieve the goals of Foregen?
  • [26:00] Who funds Foregen? What are the motivations of backers?
  • [27:45] Why large biotech and medical companies avoid moving into the foreskin regeneration space despite clear market interest.
  • [28:35] The advantage Foregen has over other companies
  • [30:20] How Foregen brings in scientific experts
  • [32:00] Does Foregen have a political stance on the issue of circumcision?
  • [33:50] Why more research is needed on the nerve endings of the foreskin
  • [35:00] Foregen’s plans to conduct research
  • [37:30] How new technology can facilitate better  studies on the foreskin
  • [39:15] The phantom limb phenomenon in circumcised men
  • [40:45] The technology exists to bring full function and feeling to somebody with damaged genitals
  • [41:10] How to support Foregen’s work

Resources:

  • Foregen’s Website
  • Foregen on Facebook / Twitter / Instagram / Linkden
  • Foregen Subreddit

Research Mentioned (there is a lot):

  • Rengeration of Vagina
  • Regeneration of the entire human epidermis using transgenic stem cells
  • Phantom Limb Article
  • Second Phantom Limb Article
  • 20,000 Nerve Ending Myth
  • Penile Skin Reconstruction 1
  • Penile Skin Reconstruction 2
  • Penile Skin Reconstruction 3
  • Tooth regeneration
  • Bondioli’s Patent
  • Foregen’s 2018 paper
  • Pelvic Reconstruction
  • Breast Reconstruction
  • Hernia Repair
  • Abdominal Wall Defects
  • Rotator Cuff Repair 1
  • Rotator Cuff Repair 2
  • Full-Thickness Skin Wounds 1
  • Full-Thickness Skin Wounds 2
  • Development of Method

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